Animal research is essential for drug advancements

Print Why Animals are Used Animals are used in research when there is a need to find out what happens in the whole, living body, which is far more complex than the sum of its parts.

Animal research is essential for drug advancements

Animal research is essential for drug advancements

Penicillin InAlexander Fleming noticed that staphylococcus bacilli would not grow on a culture medium accidentally contaminated with a mold, Pencillim notatum. But test tube experiments failed to show the antibiotic properties he expected. Ten years later, Oxford chemists Ernest Chain and Howard Florey were working on antibacterial substances.

But when Chain injected two mice with it, they remained healthy. Delighted by this apparent lack of toxicity, Florey then decided to give his full attention to penicillin.

The animal experiment Only by was enough penicillin available for testing. Eight mice were infected with a deadly dose of million streptococci bacteria.

One hour later, four of them were injected with penicillin.

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These survived but the untreated ones died. The amount of penicillin needed to treat a human is 3, times greater than for a mouse.

Without these early whole animal proofs on toxicity and effectiveness, penicillin would not have been developed further. It revolutionized the ability to treat bacterial infections, which were a major cause of death.

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This simple animal test led directly to the saving of literally millions of lives, both human and animal.

Blood transfusion The first successful blood transfusion was performed on a dog by Richard Lower in and perfected in dogs by Clotting was prevented by the addition of sodium citrate and citrated blood was shown to be safe for transfusion to dogs in The animal experiment In Richard Lewisohn determined the maximum safe concentration of citrate that could be used when transfusing blood into a dog.

The following year two doctors, Peyton Rous and Joseph Turner at the Rockefeller Institute, New York showed that blood treated with citrate and glucose could be stored for as long as three weeks in rabbits and safely transfused back into the animals.

Learn how animal testing and research has advanced human health.

Later work established longer storage times for human blood. Much blood transfusion research is done in test tubes, but animals were used to establish the safety of citrated blood. Blood transfusion is used after injury and surgery and to treat cancers and anaemia.

Open heart surgery would not be possible without it. Tuberculosis A century ago, TB was a common cause of death.

Inthere werecases in Britain. It was also endemic among farm animals.Animal research remains a cornerstone of current and future healthcare advancements. Because this is the case, removing this essential tool would make it extremely difficult, if not impossible, to find cures for countless diseases.

Alternatives to Animal Research. The hope is that such microsystems, developed with human cells, can replace costly and poorly-predictive animal tests, making the process of drug development and toxicology testing more accurate and human-relevant.

These models could be designed to mimic specific disease states and to study tissue.

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Animal research and testing are the key to the medical advances we are familiar with today and all of the advances to come. Animal testing and research has led to countless medical and scientific advancements. Foundation for Biomedical Research. Animal Research has brought about many medical benefits.

This page discusses a handful of examples where animal testing has been instrumental in the development of a medical treatment.

To set your research career to the tune of the scientific advancements, CogniBrain’s preclinical research services is a one-stop-shop for all your research needs.

Animal Testing: Humane Research from a Human Perspective – Speaking of Research

We aid you carry out advanced researches using conventional/ transgenic animal models, ex-vivo and in-vitro models. Because Ebola evolved from primate viruses, animal research is essential to the study of disease.

Ebola is a leading cause of death in wild chimpanzees and gorillas, so the role of non-human primates in developing a vaccine cannot be overstated.

Animal research generates new treatments, benefits society | UCLA